FYI, the 'cryptography' package from pypi no longer builds after this fix. (I applied the patch to the 2.7.14 source code tarball.) I don't know if that's because of the fix, or because LibreSSL 2.7.X broke 'cryptography' too:
clang -fno-strict-aliasing -g -O2 -DNDEBUG -g -fwrapv -O3 -Wall -Wstrict-prototypes -I/opt/slangs/py/include/python2.7 -c build/temp.macosx-10.13-x86_64-2.7/_openssl.c -o build/temp.macosx-10.13-x86_64-2.7/build/temp.macosx-10.13-x86_64-2.7/_openssl.o -Wconversion -Wno-error=sign-conversion
build/temp.macosx-10.13-x86_64-2.7/_openssl.c:493:10: fatal error: 'openssl/opensslv.h' file not found
#include <openssl/opensslv.h>
^~~~~~~~~~~~~~~~~~~~
1 error generated.
error: command 'clang' failed with exit status 1 |