HIST2H2BF

From Wikipedia, the free encyclopedia

H2BC18

Identifiers

H2BC18, histone cluster 2 H2B family member f, H2B clustered histone 18, HIST2H2BF

External IDs

MGI: 2448413; HomoloGene: 136264; GeneCards: H2BC18; OMA:H2BC18 - orthologs

Gene location (Human)

Chr.	Chromosome 1 (human)^[1]

Band	1q21.2	Start	149,782,689 bp^[1]
Band	1q21.2	End	149,812,373 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 3 (mouse)^[2]

Band	3\|3 F2.1	Start	96,177,068 bp^[2]
Band	3\|3 F2.1	End	96,177,448 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

bone marrow cell

testicle

blood

epithelium of colon

corpus callosum

right uterine tube

left ovary

prostate

right hemisphere of cerebellum

right ovary

Top expressed in

uterus

bone marrow

tail of embryo

genital tubercle

embryo

embryo

morula

yolk sac

zygote

mesencephalon

More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	protein heterodimerization activity DNA binding molecular function
Cellular component	chromosome nucleosome extracellular exosome nucleus nucleoplasm cytosol
Biological process	nucleosome assembly
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


440689


319189

Ensembl


ENSG00000203814


ENSMUSG00000105827

UniProt


Q5QNW6


Q64525

RefSeq (mRNA)


NM_001024599 NM_001161334


NM_175666

RefSeq (protein)


NP_001019770 NP_001154806


NP_783597

Location (UCSC)

Chr 1: 149.78 – 149.81 Mb

Chr 3: 96.18 – 96.18 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Histone H2B type 2-F is a protein that in humans is encoded by the HIST2H2BF gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000203814 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000105827 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: HIST2H2BF histone cluster 2, H2bf".

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Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
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Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Pavri R, Zhu B, Li G, et al. (2006). "Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II". Cell. 125 (4): 703–17. doi:10.1016/j.cell.2006.04.029. PMID 16713563. S2CID 2614680.
Kim SC, Sprung R, Chen Y, et al. (2006). "Substrate and functional diversity of lysine acetylation revealed by a proteomics survey". Mol. Cell. 23 (4): 607–18. doi:10.1016/j.molcel.2006.06.026. PMID 16916647.