Dante Merlino, MD, PhD
Fellow, Head & Neck Surgical Oncology & Microvascular Reconstruction | University of Pennsylvania
Former Resident, Otolaryngology - Head & Neck Surgery | Mayo Clinic
🧠 About Me
Physician–scientist and head & neck surgeon passionate about combining clinical practice, data science, and AI-driven analytics to improve surgical outcomes and healthcare efficiency.
🔬 Current Focus
- 🏥 Clinical: Head & Neck Oncology, Microvascular Reconstruction, Transoral Robotic Surgery
- 💻 Research: Surgical quality metrics, treatment deescalation of HPV-mediated oropharyngeal cancer
- 🧩 Technology: Python • SQL • LangChain • Databricks • LM Studio • Epic Clarity/Caboodle • Google Cloud Platform
🚀 Featured Projects
🧠 AI Agents for Surgical Analytics
- Developed a post-operative readmission prediction agent using
mlflowandLangGraph. - Created an “Optimization Master” that automatically rewrites SQL with early filters, CTEs, and execution plan hints.
- Integrated with Databricks
LLM endpointsfor multi-query reasoning and report generation.
📊 Healthcare Informatics & Dashboards
- Built dashboards from Epic → Databricks pipelines for quality improvement and volume tracking.
- Implemented Epic Clarity/Caboodle ETL into Databricks using structured SQL + Python workflows.
- Designed LLM-assisted documentation review and readmission classification models.
🧬 Research & Publications
- Exploring AI and large language models for clinical documentation optimization.
- Focus on AI governance, ethics, and responsible adoption in surgical practice.
🤝 Collaboration Interests
- 🧩 AI & machine learning in clinical applications
- 🏥 Databricks + Epic integration for healthcare data pipelines
- 📈 Surgical outcomes, predictive analytics, and quality registries
- ⚙️ LangChain, LangGraph, and local LLM deployments (LM Studio, Ollama)