npm i -g md5-js

md5 example.txt

md5 "hello world"

<script src="md5-min.js"></script>
<script>
    var hash = md5('hellow world');
    alert(hash);
</script>

var fs = require('fs');
var md5 = require('md5-js');

console.log(md5('hellow world'));

fs.readFile('example.txt', function(err, buf) {
  console.log(md5(buf));
});