Chris Madison
Fractional CTO · Co-Founder, Interstice Digital · Builder at the intersection of AI and Web3
20+ years scaling engineering organizations from 5 to 120+ engineers across blockchain, healthcare, and enterprise. 12 AI/ML patents. Currently building trust infrastructure for AI agents and cross-chain swap protocols.
What I'm Building
🔐 trstlyr.ai — Trust scoring system for AI agents combining Web2 and Web3 signals. Built for the Synthesis hackathon; exploring it as sustainable public infrastructure.
🤖 Application Intelligence — Transforming traditional QA into AI-powered UX feedback systems. Moving beyond test generation toward understanding how users actually experience software.
Recent Work & Repos
| Project | What It Does | Stack |
|---|---|---|
| aegis | AI agent trust scoring infrastructure | TypeScript |
| clawsino | AI agent orchestration experiments | TypeScript |
| solana-defi-indexer-rs | High-performance DeFi data indexer | Rust |
| didcomm_soldid_resolver_rs | DIDComm resolver for Solana DIDs | Rust |
| crewai-financial-analyst-crew | Multi-agent financial analysis with CrewAI | Python |
| ppe-kafka-go | Event-driven pipeline processing | Go |
Where I've Led Engineering
Long Run Advisory — Fractional CTO engagements across AI and blockchain startups
Everyrealm — VP Engineering. Scaled from 7 to 45 engineers across gaming, metaverse, and NFT infrastructure.
Interchain Foundation — VP Engineering. Led Cosmos SDK ecosystem tooling and multi-org engineering coordination.
IOG (IOHK) — Engineering leadership for Cardano ecosystem development.
PeraHealth — VP Engineering. Built real-time patient acuity scoring integrated with Epic/Cerner EHR systems.
Equideum Health — CTO/COO. HIPAA-compliant blockchain infrastructure for health data.
IBM — 16 years. Scaled WebSphere product engineering globally. Origin of 12 AI/ML patents.
Tech I Reach For
AI/ML: Claude Agent SDK · LangGraph · CrewAI · RAG pipelines · Agent orchestration
Languages: TypeScript · Rust · Go · Python · Solidity
Blockchain: Ethereum · Solana · Cosmos · Canton Network · HTLC · DID/Verifiable Credentials
Infrastructure: AWS · Supabase · Docker · Terraform · GitHub Actions
Healthcare: FHIR · HL7 · Epic/Cerner integrations · HIPAA compliance
Currently exploring: AI agent trust frameworks · Cross-chain atomic swaps · The long runs (30-50 mi/week, mountains preferred)